Anticancer potential of secondary metabolites from marine actinomycetes

Actinomycetes are the most effective microorganism antagonists. Marine actinomycetes, which may be found in shallow to deep sea sediments, have proven to be an excellent source for research. Streptomyces, Saccharopolyspora, Amycolatopsis, Micromonospora, and Actinoplanes are the major producers of commercially relevant biomolecules among its various species. Because of its extraordinary diversity and severe conditions, the marine environment attracts special attention when looking for new sources of commercially essential items; it is known to produce metabolic products of great value. Marine actinomycetes are significant for industry since they are one of the most efficient classes of secondary metabolite producers. Actinomycetes isolated from the marine environment are currently receiving a lot of interest because of the structural diversity and distinct biological activities of their secondary metabolites. They are effective producers of novel secondary metabolites with antibacterial, antifungal, anticancer, antitumor, cytotoxic, cytostatic, anti-inflammatory, anti-parasitic, anti-malaria, antiviral, antioxidant, anti-angiogenesis, and other biological actions. Marine actinomycetes are extremely promising, yielding high-quality, value-added products that will usher in a new era of bioactive compounds with medicinal and biotechnological applications. In this review, we list and describe secondary metabolites from marine actinomycetes that will be used for anticancer activity.

Keywords

Marine actinomycetes, Secondary metabolites, Anti-cancer activity, Anti-cancer potential compounds, Cancer cell lines