Formulation & Evaluation of Herbal Antiseptic Cream from Giloy

Author: Shubham R. Mali, Kalpesh D. Mahajan Vaishali R. Mahajan, Dr. Chandrakant P. Suryawanshi

Published On: 2025-03-29

The present study focuses on the extraction and evaluation of Tinospora cordifolia stem extract for its phytochemical and antimicrobial properties. The extract was obtained using the Soxhlet extraction method and subjected to phytochemical screening. The antimicrobial efficacy of the extract was assessed against Staphylococcus aureus and Bacillus subtilis, showing zones of inhibition of 8 mm and 6 mm, respectively. Based on varying extract concentrations, four antiseptic cream formulations (A1, A2, A3, and A4) were developed and evaluated for stability, spreadability, viscosity, and pH. Among all formulations, A4 exhibited superior physicochemical characteristics and was selected as the final optimized formulation. Since herbal formulations pose stability challenges due to the complexity of Phytoconstituents, further stability studies are essential to determine the shelf life and long-term efficacy of the formulation. This study highlights the potential of Tinospora cordifolia as an antimicrobial agent in topical applications and emphasizes the need for extensive stability evaluation to ensure formulation efficacy and safety over time. 

Keywords: Tinospora cordifolia, antiseptic cream, pH etc.