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Oxidative stress cataract enhancer

Author: Sheetu, Manish Kumar, Mohit Dadwal, Sahil Saini and Shankar Dev Thakur

Published On: 2021-11-24

Abstract

In many countries, cataract is the leading cause of blindness. This review article focuses on oxidative stress that leads to cataract formation. In cases of hyperglycaemia, superoxides of the mitochondria are elevated mainly by age, but also in cases of diabetes. There are different factors that leads to activation of free radicle and enhance the formation of cataract like oxidation imbalance, stress signalling, protein kinase pathway, lipid peroxidation, lens epithelial cell apoptosis. Additionally, this article includes synthetic and herbal anti-cataractous drugs that helps in preventing the formation of cataract.

Keywords

Cataract, Cataractogenesis, Oxidative stress, Oxidation, Glutathione, Aldose reductase

Keywords
Cataract Cataractogenesis Oxidative stress Oxidation Glutathione Aldose reductase
Article Information
Volume

4

Year

2021

Review Rounds

1

Article Type

Research Article

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